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Fuch’s Endothelial Dystrophy



It is an inherited condition that affects the endothelium, the delicate innermost layer of the cornea. Fuch’s Corneal Dystrophy occurs when the endothelial cells gradually deteriorate overtime. Once lost, these endothelial cells do not grow back leading to cornea clouding, swelling and impaired vision.


In the early stages of the disease, patients notice an increase in the appearance of glare and increase in sensitivity to light. As the condition progresses vision maybe blurred in the morning then sharpen as the day goes on as the condition worsens vision may appear blurry throughout the day.




Fuch’s Corneal Dystrophy affects both eyes and is slightly more common among women than men. It usually starts to develop around 30 to 40 years of age with no apparent cause. The vision becomes severely impaired and corneal transplant may be required.


We no longer perform full thickness corneal transplants for this indication. Our standard method is endothelial cell transplantation (cell transplantation). The cells are carried on its natural bed and implanted in the eye. There are couple of techniques we use the Descemet’s Stripping Endothelial Keratoplasty (DSEK) and Descemet’s Membrane Endothelial Keratoplasty (DMEK)